Research

Basic Science Faculty Research Interests

Name
Research Interests
Cory Abate–Shen Understanding the relationship between the processes that control normal development and those that lead to cancer
Asa Abeliovich The molecular mechanisms of neurodegeneration and the function and survival of dopamine receptors
Rando Allikmets Stargardt macular dystrophy and other retinal diseases
Richard Ambron Signals that mediate changes in transcription following nerve injury
Ottavio Arrancio Mechanisms underlying changes of synaptic function associated with cognitive impairment
Richard Axel Defining the logic of olfactory perception
Richard Baer The pathogenesis of hereditary breast cancer
Jonathan Barasch Developmental and cell biology of kidney organogenesis
Paulette Bernd The mechanisms underlying neuronal cell death in neurodegenerative diseases such as Parkinson’s and Alzheimer’s.
Philip W. Brandt How cooperation between the proteins of the thin and thick filaments regulates muscle contraction
J. Chloe Bulinski Function of the cytoskeleton during the cell cycle and during differentiation
Robert Burke Programmed cell death in models of Parkinsonism
Julie C. Canman Molecular mechanisms of cell division
Peter D. Canoll Mechanisms of glioma growth and invasion
Fred Chang Cell polarization, cell division and dynamics of the cytoskeleton in fission yeast
Lorraine N. Clark Genetics of neurodegenerative disease
Carlos Cordon–Cardo Understand what causes variation in cancers as a means to provide better diagnoses, prognoses, and treatment for patients
Riccardo Dalla-Favera Molecular genetics of cancer; molecular pathogenesis of lymphoma and leukemia
Thomas Diacovo Adhesive interactions between circulating blood cells and endothelium
Gilbert Di Paolo Role of phosphoinositides in organelle trafficking, cytoskeletal dynamics and disease-related processes
Fiona Doetsch The nature and function of stem cells for adult neurogenesis
Karen Duff Mouse models of Alzheimer’s Disease
Qing R. Fan Structural biology; cell surface receptor-ligand recognition
Adolfo Ferrando Understand the molecular mechanisms that sustain the proliferation and survival of leukemic cells, and to identify novel therapeutic targets for the design of highly effective, molecularly-tailored antileukemic drugs
Michael D. Gershon Structure, function and development of the enteric nervous system
James E. Goldman Glial differentiation in mammalian CNS development; progenitors in the adult CNS
Lloyd A. Greene Molecular mechanisms governing neuronal differentiation and survival
Wei Gu P53 in tumor suppression and aging
Gregg G. Gundersen The regulation and function of the microtubule cytoskeleton
Christopher Henderson Motor neuron development and pathology
Ulrich Hengst The physiological role of intra-axonal protein synthesis
Antonio Iavarone Molecular genetics of tumors derived from the nervous system
Steven G. Kernie Mechanisms and relevance of injury-induced neurogenesis
Richard H. Kessin Genetic capacity of Dictyostelium discoideum to study proteolytic mechanisms and regulation
Tae-Wan Kim Presenilin biology and molecular mechanism of Alzheimer's disease
Jan Kitajewski Wnt and Notch genes in tumorigenesis and vascular development
Ulf Klein Germinal center B-cell differentiation: Physiology and disruption in malignancy
Stavroula Kousteni Molecular studies of skeletal physiology
Anna Lasorella Molecular biology of pediatric tumors
Edward M. Laufer Regulation of steroid producing cells in the adrenal cortex
Fangming Lin 1) Stem cell-based therapy to accelerate renal repair following acute kidney injury. 2) Mechanisms of renal tubular atrophy after urinary tract obstruction.
Ronald Liem The neuronal cytoskeleton and its involvement in neurodegenerative diseases
W. Ian Lipkin Immunopathogenesis and infectious diseases
Thomas Ludwig Molecular functions of breast cancer susceptibility genes BRCA1 and BRCA2
Yinghui Mao Kinetochore microtubule attachment, chromosome movement, and mitotic checkpoint during mitosis
Carol A. Mason Molecular mechanisms of axon guidance and synaptogenesis
Cathy Mendelsohn Molecular pathways controlling development of urogenital tract
Umrao Monani Motor neuron disease - spinal muscular atrophy as a paradigm
Siddharta Mukherjee Understanding malignant and pre-malignant blood diseases such as Myelodysplastic Sydrome (MDS) and Acute Myelogenous Leukemia (AML)
Peter L. Nagy The role of transcriptional defects in neurodegenerative disorders and the use of high throughput sequencing in clinical diagnosis
Kenneth P. Olive Preclinical therapeutics in genetically engineered mouse models of pancreatic cancer
David M. Owens The contributions of stem cells and differentiated cells to epidermal cancer
Ramon Parsons The genetics of breast cancer tumorigenesis
Livio Pellizzoni RNA Biology and Motor Neuron Pathology
Liza A. Pon Cytosketetal control of organelle movements and segregation during cell division
Serge Przedbrodski Toxin-induced damage to neurotransmitter systems pertinent to movement disorders
Michael L. Shelanski Role of cytoskeleton, cell cycle machinery, and proteases in neuronal degeneration
Jose Silva Studying the Biology of Breast Cancer
Rae Silver Neurobiological basis of circadian rhythms and role of mast cells in the brain
Janet Sparrow Cell biology of retinal disorders
Steven Spitalnik The biochemistry, cell biology, and immunology of glycoproteins and glycolipids
Gloria Su Molecular genetics of head and neck squamous cell carcinoma and pancreatic ductal adenocarcinoma
Ira Tabas Cellular and molecular processes related to arterial wall biology and atherogenesis
C. Dominique Toran- Allerand The role of the steroid hormone estrogen in the developing CNS
Carol Troy The study of the molecular mechanisms of neuronal death with an emphasis on the regulation of caspase activity
Stephen Tsang Stem Cells and Reprogramming in Neuronal Degenerations
Benjamin Tycko Molecular biological studies on genomic imprinting; molecular genetics of pediatric tumors
Richard Vallee Microtubule motor proteins in axonal transport, brain developmental disease, and synaptic function
David J. Volsky HIV, neuropathogenesis, and mouse models of HIV infection and disease
Clarissa Waites Roles of protein ubiquitination in synaptic function and neurodegeneration
Hynek Wichterle The use of stem cells to study the development and function of the nervous system
Robert Winchester Autoimmunity and autoimmune disease
Howard J. Worman The studies of the inner nuclear membrane and its proteins
Ai Yamamoto Protein trafficking in Huntington’s disease and other neurological disorders
Darrell Yamashiro The role of angiogenesis in promoting the growth and metastasis of pediatric solid tumors
Shan Zha The molecular mechanisms of DNA damage response and their roles in lymphocyte gene-rearrangement
Bin Zheng Signal Transduction and Cancer Cell metabolism in Melanoma
 
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