Resident Awards, Select Publications, and Presentations

Pathology residents at 2024 USCAP
Niyati Desai, PGY3 resident, presenting at USCAP 2024
Yin Guo, winner of Pathology-In-Training Travel Award at USCAP 2024. (5th from right with other winners).
CUIMC Pathology Resident Presentation
CUIMC Pathology Resident Presentation
CUIMC Pathology Resident Presentation
Simona De Michele, MD
CU Pathology resident presentation 1
CU Pathology resident presentation 2
CU Pathology resident presentation 3
CUIMC Pathology Resident Presentation

Awards

  • Ian Mellis, 2024 ACLPS Paul E. Strandjord Young Investigator Award.
  • Saliba, M, ADASP Surgical Pathology Award, USCAP 2023
  • Besharati, S, 2022 Emerging Liver Scholar Award from AASLD
  • De Michele S., Pathologist-in-Training Research Award by the Papanicolaou Society for Cytopathology, Best Abstract Presented at USCAP 2021.
  • Smithgall, MC, Association of Pathology Chairs Society of ’67 Scholar 2020.
  • Smithgall, MC, Young Investigator Award Recipient ACLPS 2019.
  • Katsyv, I, Physician-in-Training Award, Best Oral Abstract Presentation, American Society of Dermatopathology Annual Meeting 2019.
  • Parrott, A, Awarded the Paul E. Strandjord Young Investigator Award at ACLPS 2016.

Recent Publications

  • Wang, Q.*, Guo, Y.*, Bowen, A.*, Mellis, I.A.*, Valdez, R., Gherasim, C., Gordon, A., Liu, L., Ho, D.D., 2023. XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against emerging SARS-CoV-2 variants. Cell Host & Microbe 32, no. 3 (2024): 315-321.
  • Tepp JA, Remotti F, Szabolcs MJ, Saqi A. Histological characterisation of pulmonary monkeypox virus infection in a patient with AIDS. Histopathology. Published online February 29, 2024. doi:10.1111/his.15164
  • Tepp JA, Agaram NP, Chang JC, Linos K. Cellular Cutaneous Epithelioid Hemangioma Harboring the Rare GATA6::FOXO1 Gene Fusion. Am J Dermatopathol. Published online March 8, 2024. doi:10.1097/DAD.0000000000002647
  • Mishra N, Strom MA, Ng J, Jain K, Thakkar R, Shreyas J, Pereira M, Shah L, Grossman ME, Lee MJ, De Michele S., Silvers DN, Faust PL, Lipkin WI, Gallitano Human Polyomavirus 9—An Emerging Cutaneous and Pulmonary Pathogen in Solid Organ Transplant Recipients. JAMA Dermatol. 2022;158(3):293–298. doi:10.1001/jamadermatol.2021.5853
  • D’Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells. 2021; 10(9):2293. https://doi.org/10.3390/cells10092293
  • Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I*, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro DT, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy N, Suárez-Fariñas M, Bakhoum SF, Bram Y, Borczuk A, Guo XV, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J, Izar B. A molecular single-cell lung atlas of lethal COVID-19. Nature. 2021 Apr 29.
    *co-first author
  • Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, Segerstolpe Å, Abbondanza D, Fleming SJ, Subramanian A, Montoro DT, Jagadeesh KA, Dey KK, Sen P, Slyper M, Pita-Juárez YH, Phillips D, Biermann J, Bloom-Ackermann Z, Barkas N, Ganna A, Gomez J, Melms JC, Katsyv I*, Normandin E, Naderi P, Popov YV, Raju SS, Niezen S, Tsai LT, Siddle KJ, Sud M, Tran VM, Vellarikkal SK, Wang Y, Amir-Zilberstein L, Atri DS, Beechem J, Brook OR, Chen J, Divakar P, Dorceus P, Engreitz JM, Essene A, Fitzgerald DM, Fropf R, Gazal S, Gould J, Grzyb J, Harvey T, Hecht J, Hether T, Jané-Valbuena J, Leney-Greene M, Ma H, McCabe C, McLoughlin DE, Miller EM, Muus C, Niemi M, Padera R, Pan L, Pant D, Pe'er C, Pfiffner-Borges J, Pinto CJ, Plaisted J, Reeves J, Ross M, Rudy M, Rueckert EH, Siciliano M, Sturm A, Todres E, Waghray A, Warren S, Zhang S, Zollinger DR, Cosimi L, Gupta RM, Hacohen N, Hibshoosh H, Hide W, Price AL, Rajagopal J, Tata PR, Riedel S, Szabo G, Tickle TL, Ellinor PT, Hung D, Sabeti PC, Novak R, Rogers R, Ingber DE, Jiang ZG, Juric D, Babadi M, Farhi SL, Izar B, Stone JR, Vlachos IS, Solomon IH, Ashenberg O, Porter CBM, Li B, Shalek AK, Villani AC, Rozenblatt-Rosen O, Regev A. COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature. 2021 Apr 29.
    *co-second author
  • Valk JE, Chong AM, Uhlemann AC, Debelenko L. Detection of SARS-CoV-2 in placental but not fetal tissues in the second trimester. J Perinatol. 2020 Nov 30:1-3. doi: 10.1038/s41372-020-00877-8. Online ahead of print.
  • Debelenko L, Katsyv I, Chong AM, Peruyero L, Szabolcs M, Uhlemann AC. Trophoblast Damage with Acute and Chronic Intervillositis: Disruption of Placental Barrier by SARS-CoV-2. Hum Pathol. 2020 Dec 12:S0046-8177(20)30256-2. doi: 10.1016/j.humpath.2020.12.004. Online ahead of print.
  • Ofori K, Bhagat G, Rai AJ. Exosomes and Extracellular Vesicles as Liquid Biopsy Biomarkers in Diffuse Large B-cell Lymphoma (DLBCL): Current State of the Art and Unmet Clinical Needs [published online ahead of print, 2020 Oct 20]. Br J Clin Pharmacol. 2020;10.1111/bcp.14611. doi:10.1111/bcp.14611
  • Kunnath V. S., Larsen B. T., Bhagat G., De Michele S., Santoriello D., Coley S. M., Colby T. V., Saqi A. “Masson Thrichrome and Sulfated Alcian Blue Stains: Utility in Establishing Light Chain deposition Disease and Distinguishing from Amyloidosis in the Lung”. Am J Surg Pathol 2020;00:000–000. doi: 10.1097/PAS.0000000000001593
  • Ashima Nayyar, Matthew I Saleem, Mine Yilmaz, Margaret DeFranco, Gila Klein, Kristine M Elmaliki, Elena Kowalsky, Prodyot K Chatterjee, Xiangying Xue, Radhika Viswanathan, Andrew J Shih, Peter K Gregersen, Christine N Metz. Menstrual Effluent Provides a Novel Diagnostic Window on the Pathogenesis of Endometriosis. Frontiers in Reproductive Health. 2020; 2:3.
  • Ofori K, Soderquist CR, Murty VV, et al. The clinical and pathological features of plasma cell myeloma post solid organ transplantation [published online ahead of print, 2020 Aug 30]. Am J Hematol. 2020;10.1002/ajh.25988.
  • Mine M Yilmaz, Matthias J Szabolcs, Larisa J Geskin, George W Niedt. An Autopsy Review: “COVID Toes”. The American Journal of Dermatopathology. 2020; AJD-D-20-00359.
  • Utukuri, P, Lefkowitch, JH, Erde S, Smithgall, M, Makkar, J, Weintraub, J, Bernd, P. Student-Authored Autopsy Reports of Anatomical Donors, Their First Patients. Medical Science Educator. 2020.
  • De Michele S., Remotti H., Lagana S., Del Portillo A., Szabolcs M., Saqi A., “SATB2 in Neoplasms of Lung, Pancreatobiliary & Gastrointestinal Origins”.  Am J Clin Pathol. 2020 Sep 11; aqaa118. doi: 10.1093/ajcp/aqaa118
  • De Michele S., Sun Y., Yilmaz M., Katsyv I., Salvatore M., Dzierba A., Marboe C., Brodie D., Patel N., Garcia C., Saqi A. “Forty Post-Mortem Examinations in Covid-19 Patients: Two Distinct Pathologic Phenotypes and Correlation with Clinical and Radiological Findings”. Am J Clin Pathol. 2020 Sep 2 : aqaa156. doi: 10.1093/ajcp/aqaa156
  • Lagana S., Kudose S., Iuga A., Lee M., Fazlollahi L., Remotti H., Del Portillo A., De Michele S., Koehne de Gonzalez A., Saqi A., Khairallah P., Chong  A., Park H., Uhlemann A., Lefkowitch J., Verna E. “Hepatic Pathology in Patients Dying of COVID-19: A Series of 40 Cases Including Clinical, Histologic, and Virologic Data”. Modern Pathology 2020. doi.org/10.1038/s41379-020-00649-x
  • Smithgall MC, Liu-Jarin X, Hamele-Bena D, Cimic A, Mourad M, Debelenko L, Chen X. Third Trimester Placentas of SARS-CoV-2-Positive Women: Histomorphology, including Viral Immunohistochemistry and in Situ Hybridization. Histopathology. 2020.
  • Smithgall MC, Scherberkova I, Whittier S, Green DA. Comparison of Cepheid Xpert Xpress and Abbott ID Now to Roche cobas for the Rapid Detection of SARS-CoV-2. J Clin Virol. 2020;128:104428.
  • Smithgall MC, Dowlatshahi M, Spitalnik SL, Hod EA, Rai AJ. Types of Assays for SARS-CoV-2 Testing: A Review, Lab Med, 2020, Jul 13: lmaa039.
  • Smithgall MC, Whittier S, Fernandes H. Laboratory Testing of SARS CoV-2: A New York Institutional Experience. Advances in Molecular Pathology. 2020.
  • Chen DA*, Koehne de Gonzalez A*, Fazlollahi L, Coffey A, Remotti HE, Lagana SM. In situ hybridisation for albumin RNA in paediatric liver cancers compared with common immunohistochemical markers. J Clin Pathol. 2020 May 29:jclinpath-2020-206663. *co-first authors
  • Alina C Iuga, Charles C Marboe, Mine M Yilmaz, Jay H Lefkowitch, Cosmin Gauran, Stephen M Lagana. Adrenal vascular changes in COVID-19 autopsies. Archives of Pathology & Laboratory Medicine. 2020; doi.org/10.5858/arpa.2020-0248-LE.
  • Lagana M. S., Simona De Michele, Lee J. M., Emond J. C., Griesemer A. D., Tulin-Silver S. A., Verna E. C, Mercedes M., Lefkowitch J. H. “COVID-19 Associated Hepatitis Complicating Recent Living Donor Liver Transplantation, Arch Pathol Lab Med, 2020 Apr 17. doi: 10.5858/arpa.2020-0186-SA
  • Trager MH, Queen D, Chen D, Hodak E, Geskin LJ. Demodex-induced follicular mucinosis of the head and neck mimicking folliculotropic mycosis fungoides. JAAD Case Rep. 2020;6(4):266-272. Published 2020 Mar 24. doi:10.1016/j.jdcr.2020.01.014
  • Al-Dalahmah O, Sosunov AA, Shaik A, Ofori K, Liu Y, Vonsattel JP, Adorjan I, Menon V, Goldman JE. Single-nucleus RNA-seq identifies Huntington disease astrocyte states. Acta Neuropathol Commun. 2020 Feb 18;8(1):19. doi: 10.1186/s40478-020-0880-6. PMID: 32070434; PMCID: PMC7029580.
  • Smithgall M, Maykowski P, Zachariah P, Oberhardt M, Vargas C, Reed C, LaRussa, P, Saiman L, Stockwell MS. (2020) Epidemiology, clinical features, and resource utilization associated with respiratory syncytial virus in the community and hospital. Influenza Other Respir Viruses. 2020;14(3):247-256.
  • Al-Dalahmah O., De Michele S., Sperling D., O’Toole K., Iuga A., “Intrahepatic mass-forming extramedullary hematopoiesis in a patient with sickle cell disease: case report and literature review”. AJSP: Reviews & Reports: January/February 2020 - Volume 25 - Issue 1 - p 48-51, doi: 10.1097/PCR.0000000000000360
  • Tejero R, Huang Y, Katsyv I, Kluge M, Lin JY, Tome-Garcia J, Daviaud N, Wang Y, Zhang B, Tsankova NM, Friedel CC, Zou H, Friedel RH.  Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment.  EBioMedicine, vol 42, April 2019, 252-269.
  • Ansa GA, Ofori KN, Houphouet EE, et al. Hepatitis B vaccine uptake among healthcare workers in a referral hospital, Accra. Pan Afr Med J. 2019;33:96. Published 2019 Jun 10. doi:10.11604/pamj.2019.33.96.18042
  • Ofori K, Fernandes H, Cummings M, Colby T, Saqi A. Benign metastasizing leiomyoma presenting with miliary pattern and fatal outcome: Case report with molecular analysis & review of the literature. Respir Med Case Rep. 2019;27:100831. Published 2019 Mar 28. doi:10.1016/j.rmcr.2019.100831
  • Yen-Hua Chen*, Radomir Kratchmarov*, Wen-Hsuan W Lin*, Nyanza J Rothman, Bonnie Yen, William C Adams, Simone A Nish, Jeffrey C Rathmell, Steven L Reiner. Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway. Cell reports. 2018; 22(4): 860  *co-first authors
  • Diane E Griffin, Wen-Hsuan W Lin, Ashley N Nelson. Understanding the causes and consequences of measles virus persistence. F1000Research. 2018; 7: 237.
  • Tome-Garcia J, Erfani P, Nudelman G, Tsankov A, Katsyv I, Tejero R, Zhang B, Walsh M, Friedel R, Zaslavasky E, Tsankova N.  Chromatin accessibility uncovers TEAD1 as a regulator of migration and EGFR expression in human glioblastoma.  Nature Communications 9(1), 2018.
  • Zhou X, Wang M, Katsyv I, Irie HY, Zhang B.  EMUDRA:  Ensemble of Multiple Drug Repositioning Approaches to Dramatically Improve Prediction Accuracy.  Bioinformatics 34(18), 2018.
  • Forest SK, Vossoughi SR, Connelly C, Stotler BA. Automated laboratories: when technology needs a human touch. The Journal of Applied Laboratory Medicine. 2018; 2(6): 977-979.
  • Vossoughi SR, Perez G, Whitaker BI, Fung MK, Stotler B. Analysis of pediatric adverse reactions to transfusions. Transfusion. 2018; 58(1): 60-69.
  • Kunnath-Velayudhan S, Porcelli SA.Isolation of intact RNA from murine CD4+ T cells after intracellular cytokine staining and fluorescence-activated cell sorting. J Immunol Methods. 2018 May;456:77-80
  • Mayuko Uehara, Zhabiz Solhjou, Naima Banouni, Vivek Kasinath, Ye Xiaqun, Li Dai, Osman Yilmam, Mine Yilmaz, Takaharu Ichimura, Paulo Fiorina, Paulo N Martins, Shunsuke Ohori, Indira Guleria, Omar H Maarouf, Stefan G Tullius, Martina M Mcgrath, Reza Abdi. Ischemia augments alloimmune injury through IL-6-driven CD4+ alloreactivity. Scientific Reports. 2018; 8, Article number: 2461
  • Maykowski P, Smithgall M, Zachariah P, Oberhardt M, Vargas C, Reed C, Demmer RT, Stockwell MS, Saiman L. (2018) Seasonality and clinical impact of human parainfluenza viruses. Influenza Other Respir Viruses. 12(6): 706-716.
  • De Michele S., Vittorio, J., Thomas, T., Diaz, G., Lefkowitch, J., Lagana, S. “A Rare Case of Neonatal Intrahepatic Cholestasis Caused by Citrin Deficiency in the United States”. AJSP: Reviews & Reports. 23(5):214-216, September/October 2018

Recent Presentations

  • De Michele S., Tiscornia-Wasserman P., Sung S. “Machine Learning/Convolutional Neural Network in Fluid Cytology for Predicting Malignancy”, 110th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Mar 13 - Mar 18 2021.
  • Mine M Yilmaz, Yvette Tanhehco. Unusually Severe Course of Autoimmune Hemolytic Anemia/Cold Agglutinin Disease: A Case Report. ASCP 2020, Virtual.
  • Smithgall MC, Remotti, H, Mansukhani M, Hsiao S, Liu-Jarin X, Fernandes H. Evaluation of Dual MMR IHC and MSI PCR Testing for Gynecologic Cancers.  Poster Presentation at United States and Canadian Academy of Pathology (USCAP) Los Angeles, CA, 2020
  • De Michele S., Katsyv I., Purushothaman S., Remotti H., “Immunohistochemical and mRNA Analysis of SATB2 Expression in Neuroendocrine Neoplasms of Pancreas and Midgut”, 109th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Los Angeles Convention Center, Los Angeles, California, Feb 29 - Mar 05 2020.
  • De Michele S., Purushothaman S., Hills C., Komissarova E., Del Portillo  A., Sepulveda L. J., Sepulveda R. A., “Spatial Characterization of p53 and p16 Expression in Barret’s Esophagus, Dysplasia and Adenocarcinoma with Quantitative Multiplex Immunofluorescence Image Analysis”, 109th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Los Angeles Convention Center, Los Angeles, California, Feb 29 - Mar 05 2020.
  •  Katsyv I, Niedt GW, “Differential Network Analysis of Melanoma Transcriptomes Identifies Metastasis-Associated Coexpression Modules.” United States and Canadian Academy of Pathology (USCAP) 109th Annual Meeting.  Los Angeles, CA.  March 2020.  Poster.
  • Purushothaman S., De Michele S., Katsyv I., Remotti H.,  “Clinical Utility of Semiquantitative Evaluation of Estrogen and Progesterone Receptor Immunohistochemistry and mRNA Analysis in Neuroendocrine Tumors of the Pancreas and Midgut”, 109th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Los Angeles Convention Center, Los Angeles, California, Feb 29 - Mar 05 2020.
  • Katsyv I, Wang M, Song WM, Zhou X, Zhang B. “Integrated Networks Dissect the Molecular Biology of Estrogen Receptor-Positive Breast Cancers.”  Association for Molecular Pathology 2019 Annual Meeting.  Baltimore, MD.  November 2019.  Poster.
  • Chen DA, Katsyv I, Sepulveda JL, Sepulveda A. “Differential Network Analysis Identified Differences In Tumor Immune Response Between Colon and Rectal Adenocarcinomas.”  Association for Molecular Pathology 2019 Annual Meeting.  Baltimore, MD.  November 2019.  Poster.
  • Miller ML, Katsyv I, Fernandes H, Hsiao SJ, Mansukhani M. “Whole Exome Sequencing and Transcriptome Sequencing of Pediatric Ependymomas:  A Single Institution Experience.” Association for Molecular Pathology 2019 Annual Meeting.  Baltimore, MD.  November 2019.  Poster.
  • Katsyv I, Niedt GW. “Network Analysis of Cutaneous Squamous Cell Carcinoma Transcriptomes Implicates the TEAD Family of Transcription Factors in Perineural Invasion.” American Society of Dermatopathology 2019 Annual Meeting.  San Diego, CA.  October 2019.  Oral presentation.
  • Smithgall, MC, et al. Multi-Center Evaluation of the Accelerate PhenoTM System for Identification and Antimicrobial Susceptibility Testing of Gram-negative Bacteria in a Region with High Rates of Antimicrobial Resistance Oral Presentation at Academy of Clinical Laboratory Physicians and Scientists (ACLPS) Salt Lake City, UT, 2019
  • De Michele S., Remotti H., Del Portillo A., Szabolcs M., Saqi A., “Lung adenocarcinoma with mucin: role of SATB2 in assessing for mucinous colorectal metastasis”. 108th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Gaylord National Resort and Convention Center, National Harbor, MD, 16-21 March 2019.
  • De Michele S., Lagana S., Hsiao S., Remotti H., “SATB2 expression in primary pancreatobiliary and gastrointestinal neoplasms”. 108th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), Gaylord National Resort and Convention Center, National Harbor, MD, 16-21 March 2019.
  • Shajo Kunnat Velayudhan, Michael F. Goldberg, Neeraj Saini, Tony Ng, Christopher Johndrow, Alison Joy Johnson and Steven A. Porcelli. Generation of IL-3 secreting T helper cells is associated with microbial challenge at barriers and IL-1 family of cytokines. AAI 2018, Austin TX